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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 835770Generated: November 4, 2026

Tetrahydrofuran → 2,2,2-Trifluoro-1-{5-[(trimethylsilyl)ethynyl]-2-thienyl}ethanone

https://huagongshe.com/reaction/835770

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
Reactant2-BromothiopheneHCID 13851—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant1-(5-Bromothiophen-2-yl)-2,2,2-trifluoroethan-1-oneHCID 19971587—
Product2,2,2-Trifluoro-1-{5-[(trimethylsilyl)ethynyl]-2-thienyl}ethanoneHCID 68507078—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-bf4e9bd3b1e64e8dad1f867e62794fd1
Source noteTest data from https://doi.org/10.1039/C8SC04228D