5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid → 5-cyclopropyl-6-(cyclopropylmethoxy)-N-[2-cyclopropyl-1-(1,3-thiazol-2-yl)ethyl]pyridine-2-carboxamide
Reaction equation
[CH:18]1([CH2:21][CH:22]([c:23]2[s:24][cH:25][cH:26][n:27]2)[NH:28][C:29](=[O:30])[c:31]2[n:32][c:33]([O:43][CH2:44][CH:45]3[CH2:46][CH2:47]3)[c:34]([CH:37]3[CH2:38][CH2:39][O:42][CH2:41][CH2:40]3)[cH:35][cH:36]2)[CH2:19][CH2:20]1.[CH:1]1([c:2]2[cH:3][cH:4][c:5]([C:6]([OH:7])=[O:8])[n:9][c:10]2[O:11][CH2:12][CH:13]2[CH2:14][CH2:15]2)[CH2:16][CH2:17]1>>[CH:18]1([CH2:21][CH:22]([c:23]2[s:24][cH:25][cH:26][n:27]2)[NH:28][C:29](=[O:30])[c:31]2[n:32][c:33]([O:43][CH2:44][CH:45]3[CH2:46][CH2:47]3)[c:34]([CH:37]3[CH2:38][CH2:39]3)[cH:35][cH:36]2)[CH2:19][CH2:20]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d9ae427fbc51448eac3b282b61abd9d4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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