5-Amino-6-chloro-2-methylimidazo[1,2-a]pyridine-8-carboxylic acid → 5-Amino-6-chloro-2-methyl-N-{[1-(2-methoxy-2-methylpropyl)piperidin-4-YL]methyl}imidazo[1,2-A]pyridine-8-carboxamide
Reaction equation
[CH3:16][O:17][C:18]([CH2:19][N:20]1[CH2:21][CH2:22][CH:23]([CH2:26][NH2:27])[CH2:24][CH2:25]1)([CH3:28])[CH3:29].[NH2:1][c:2]1[c:3]([Cl:15])[cH:4][c:5]([C:12](=[O:13])[OH:14])[c:6]2[n:7]1[cH:8][c:9]([CH3:11])[n:10]2>>[NH2:1][c:2]1[c:3]([Cl:15])[cH:4][c:5]([C:12](=[O:14])[NH:27][CH2:26][CH:23]2[CH2:22][CH2:21][N:20]([CH2:19][C:18]([O:17][CH3:16])([CH3:28])[CH3:29])[CH2:25][CH2:24]2)[c:6]2[n:7]1[cH:8][c:9]([CH3:11])[n:10]2Participants
3
Sources & evidence
- ORD record
- ord-95786733ee57480ca6f12d177798232a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…