Tert-butyl 3-(2-methyl-1,3-thiazol-4-yl)pyrrolidine-1-carboxylate → 2-Methyl-4-(pyrrolidin-3-yl)-1,3-thiazole
Reaction equation
[CH3:13][c:14]1[s:15][cH:16][c:17]([CH:19]2[CH2:20][N:21]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:22][CH2:23]2)[n:18]1.[F:1][c:2]1[cH:3][n:4][cH:5][c:6]([CH:7]2[CH2:8][CH2:9][NH:10][CH2:11]2)[cH:12]1.[F:31][c:32]1[cH:33][c:34]([CH:35]2[CH2:36][CH2:37][N:38]([C:39]([O:40][C:41]([CH3:42])([CH3:43])[CH3:44])=[O:45])[CH2:46]2)[cH:47][n:48][cH:49]1>>[CH3:13][c:14]1[s:15][cH:16][c:17]([CH:19]2[CH2:20][NH:21][CH2:22][CH2:23]2)[n:18]1Participants
4
Sources & evidence
- ORD record
- ord-d351585d034e4b36916b57c6dcbdac4e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…