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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 836249Generated: October 30, 2026

Acetic Acid → 4-hydroxy-2-phenethyl-2-phenyl-5-[[2-(trifluoromethyl)phenyl]methyl]-3H-pyran-6-one

https://huagongshe.com/reaction/836249

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantSodium ionHCID 923—
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantAcetone CyanohydrinHCID 6406—
ReactantTriethylamineHCID 8471—
Reactant2-(Trifluoromethyl)benzoyl chlorideHCID 67561—
ReactantCyano-borohydrideHCID 498716—
Reactant5,6-dihydro-4-hydroxy-6-phenyl-6-(2-phenylethyl)-2H-pyran-2-oneHCID 54682301—
Product4-hydroxy-2-phenethyl-2-phenyl-5-[[2-(trifluoromethyl)phenyl]methyl]-3H-pyran-6-oneHCID 54714075—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-44ac790043464d1a94571a084fcd5324
Source noteTest data from https://doi.org/10.1039/C8SC04228D