Potassium Cation → Tert-butyl {4-[(3-amino-7-bromoquinolin-4-ylamino)methyl]benzyl}carbamate

HRID 836303Notes

Reaction equation

HRID 836303 reaction equation
[Br:9][c:10]1[cH:11][cH:12][c:13]2[c:14]([NH:23][CH2:24][c:25]3[cH:26][cH:27][c:28]([CH2:29][NH:30][C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[cH:38][cH:39]3)[c:15]([N+:20]([O-:21])=[O:22])[cH:16][n:17][c:18]2[cH:19]1.[C:3](=[O:4])([O-:5])[O-:6].[CH2:1][CH3:2].[Cl:41][CH2:42][Cl:43].[K+:7].[K+:8].[OH2:40]>>[Br:9][c:10]1[cH:11][cH:12][c:13]2[c:14]([NH:23][CH2:24][c:25]3[cH:26][cH:27][c:28]([CH2:29][NH:30][C:31]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:37])[cH:38][cH:39]3)[c:15]([NH2:20])[cH:16][n:17][c:18]2[cH:19]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 962WaterHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 123138EthylHCID 21984421Tert-butyl {4-[(7-bromo-3-nitroquinolin-4-ylamino)methyl]benzyl}carbamate

Product 1

HCID 21984367Tert-butyl {4-[(3-amino-7-bromoquinolin-4-ylamino)methyl]benzyl}carbamate

Sources & evidence

ORD record
ord-c6d6166a82634049a0b872f712a68e8d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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