5-Bromo-2-thiophenesulfonamide → 5-[8-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylethynyl]-thiophene-2-sulfonic acid amide

HRID 836314Notes

Reaction equation

HRID 836314 reaction equation
[Br:26][c:27]1[cH:28][cH:29][c:30]([S:32](=[O:33])(=[O:34])[NH2:35])[s:31]1.[C:1](#[CH:2])[c:3]1[cH:4][n:5][c:6]2[n:7]1[cH:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]>>[C:1](#[C:2][c:27]1[cH:28][cH:29][c:30]([S:32](=[O:33])(=[O:34])[NH2:35])[s:31]1)[c:3]1[cH:4][n:5][c:6]2[n:7]1[cH:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]

Participants

3

Reactant 2

HCID 12413045-Bromo-2-thiophenesulfonamideHCID 866080113-Ethynyl-8-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine

Product 1

HCID 167384635-[8-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylethynyl]-thiophene-2-sulfonic acid amide

Sources & evidence

ORD record
ord-0909d728237040b985ec1fc5b3974fe6
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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