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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 836336Generated: October 25, 2026

Dimethylformamide → t-Butyl 5-(6-hydroxymethylpyridin-2-yl)pent-4-ynoate

https://huagongshe.com/reaction/836336

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTert-ButylamineHCID 6385—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant(6-Bromopyridin-2-yl)methanolHCID 3517811—
Reactant4-Pentynoic acid, 1,1-dimethylethyl esterHCID 10877341—
ReactantHCID 178420554HCID 178420554—
Productt-Butyl 5-(6-hydroxymethylpyridin-2-yl)pent-4-ynoateHCID 58105203—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-00fc628a8fda4bcb8d6f056647f53d2f
Source noteTest data from https://doi.org/10.1039/C8SC04228D