6'-Bromo-5''-methyl-3'H-dispiro[cyclobutane-1,2'-indene-1',2''-imidazol]-4''-amine → US8865911, 57 Isomer 1

HRID 836351Notes

Reaction equation

HRID 836351 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:12]([cH:13]1)[C:11]1([C:7]3([CH2:6]2)[CH2:8][CH2:9][CH2:10]3)[N:14]=[C:15]([CH3:19])[C:16]([NH2:18])=[N:17]1.[C:20](#[C:21][CH3:22])[c:23]1[cH:24][c:25]([B:29]([OH:30])[OH:31])[cH:26][n:27][cH:28]1>>[c:2]1(-[c:25]2[cH:24][c:23]([C:20]#[C:21][CH3:22])[cH:28][n:27][cH:26]2)[cH:3][cH:4][c:5]2[c:12]([cH:13]1)[C:11]1([C:7]3([CH2:6]2)[CH2:8][CH2:9][CH2:10]3)[N:14]=[C:15]([CH3:19])[C:16]([NH2:18])=[N:17]1

Participants

3

Reactant 2

HCID 573866666'-Bromo-5''-methyl-3'H-dispiro[cyclobutane-1,2'-indene-1',2''-imidazol]-4''-amineHCID 574164825-(1-Propynyl)pyridine-3-boronic Acid (contains varying amounts of Anhydride)

Product 1

HCID 57386668US8865911, 57 Isomer 1

Sources & evidence

ORD record
ord-faaaa27df1e24f61802efdee1f8671a0
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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