Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 836360Generated: October 30, 2026

Tetrahydrofuran → Methyl 4-amino-2-chloro-5-((trimethylsilyl)ethynyl)benzoate

https://huagongshe.com/reaction/836360

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantBenzoic acid, 4-amino-2-chloro-5-iodo-, methyl esterHCID 11839203—
ProductMethyl 4-amino-2-chloro-5-((trimethylsilyl)ethynyl)benzoateHCID 59625799—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-aff5c3d51a284cc7a58d9cebbe5e9fc2
Source noteTest data from https://doi.org/10.1039/C8SC04228D