4-Methylthiophene-2-sulfonyl chloride → HCID 57989979, compound

HRID 836717Notes

Reaction equation

HRID 836717 reaction equation
[CH3:25][c:26]1[cH:27][c:28]([S:31](=[O:32])(=[O:33])[Cl:34])[s:29][cH:30]1.[NH2:1][c:2]1[c:3]([F:24])[c:4](-[c:8]2[n:9][c:10]([C:20]([CH3:21])([CH3:22])[CH3:23])[s:11][c:12]2-[c:13]2[n:14][c:15]([NH2:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1>>[NH:1]([c:2]1[c:3]([F:24])[c:4](-[c:8]2[n:9][c:10]([C:20]([CH3:21])([CH3:22])[CH3:23])[s:11][c:12]2-[c:13]2[n:14][c:15]([NH2:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1)[S:31]([c:28]1[cH:27][c:26]([CH3:25])[cH:30][s:29]1)(=[O:32])=[O:33]

Participants

3

Reactant 2

HCID 134257144-Methylthiophene-2-sulfonyl chlorideHCID 579897094-[4-(3-Amino-2-fluorophenyl)-2-(1,1-dimethylethyl)-1,3-thiazol-5-yl]-2-pyrimidinamine

Product 1

HCID 57989979HCID 57989979, compound

Sources & evidence

ORD record
ord-04cd436a346f47ad9b3ccb2c39dfa318
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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