Nipecotic Acid → 1-[3-Fluoro-4-[5-(1-phenylcyclopropyl)-[1,3]thiazolo[5,4-b]pyridin-2-yl]benzoyl]piperidine-3-carboxylic acid
Reaction equation
[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][c:10]1-[c:11]1[s:12][c:13]2[n:14][c:15]([C:20]3([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:21][CH2:22]3)[cH:16][cH:17][c:18]2[n:19]1.[NH:29]1[CH2:30][CH:31]([C:35](=[O:36])[OH:37])[CH2:32][CH2:33][CH2:34]1>>[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[N:29]2[CH2:30][CH:31]([C:35](=[O:36])[OH:37])[CH2:32][CH2:33][CH2:34]2)[cH:8][cH:9][c:10]1-[c:11]1[s:12][c:13]2[n:14][c:15]([C:20]3([c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[CH2:21][CH2:22]3)[cH:16][cH:17][c:18]2[n:19]1Participants
3
Sources & evidence
- ORD record
- ord-627eee20f5cb4f6a8c343275d2f8630a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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