5-(Benzyloxy)-2-methylbenzoic acid → 2-(1-{[5-(Benzyloxy)-2-methylphenyl]carbonyl}piperidin-4-yl)-5-[3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl]-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one
Reaction equation
[CH2:30]([c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1)[O:37][c:38]1[cH:39][cH:40][c:41]([CH3:47])[c:42]([C:43](=[O:44])[OH:45])[cH:46]1.[CH:1]1([CH2:4][O:5][c:6]2[cH:7][c:8]([C:16]3=[N:20][N:19]([CH:21]4[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]4)[C:18](=[O:27])[C:17]3([CH3:28])[CH3:29])[cH:9][cH:10][c:11]2[O:12][CH:13]([F:14])[F:15])[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][O:5][c:6]2[cH:7][c:8]([C:16]3=[N:20][N:19]([CH:21]4[CH2:22][CH2:23][N:24]([C:43]([c:42]5[c:41]([CH3:47])[cH:40][cH:39][c:38]([O:37][CH2:30][c:31]6[cH:32][cH:33][cH:34][cH:35][cH:36]6)[cH:46]5)=[O:44])[CH2:25][CH2:26]4)[C:18](=[O:27])[C:17]3([CH3:28])[CH3:29])[cH:9][cH:10][c:11]2[O:12][CH:13]([F:14])[F:15])[CH2:2][CH2:3]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6f1be69e1ea4415db2490ab52b7af12f
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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