Methyl iodide → 8-Methyl-2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decane-1,7-dione
Reaction equation
[CH3:24][I:25].[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:21])[C:12]3([CH2:13][CH2:14]2)[CH2:15][C:16](=[O:20])[NH:17][CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:22])[F:23]>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([N:10]2[C:11](=[O:21])[C:12]3([CH2:13][CH2:14]2)[CH2:15][C:16](=[O:20])[N:17]([CH3:24])[CH2:18][CH2:19]3)[cH:8][cH:9]1)([F:22])[F:23]Participants
3
Sources & evidence
- ORD record
- ord-d9bfec59089d44e3b4141a3af330258d
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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