Dichloromethane → Methyl 3-[(2-methylpropan-2-yl)oxycarbonylamino]-2-oxo-12-(4-phenylphenyl)-11-thia-1-azabicyclo[10.2.1]pentadec-8-ene-14-carboxylate

HRID 837089Notes

Reaction equation

HRID 837089 reaction equation
[CH2:1]([CH:2]=[CH2:3])[S:4][C:5]1([c:31]2[cH:32][cH:33][c:34](-[c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[cH:35][cH:36]2)[CH2:6][CH:7]([C:27](=[O:28])[O:29][CH3:30])[N:8]([C:10]([CH:11]([CH2:12][CH2:13][CH2:14][CH2:15][CH:16]=[CH2:17])[NH:18][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[CH2:9]1.[Cl:53][CH2:54][Cl:55].[SH:43][c:44]1[n:45][cH:46][cH:47][cH:48][c:49]1[C:50]([OH:51])=[O:52]>>[CH2:1]1[S:4][C:5]2([c:31]3[cH:32][cH:33][c:34](-[c:37]4[cH:38][cH:39][cH:40][cH:41][cH:42]4)[cH:35][cH:36]3)[CH2:6][CH:7]([C:27](=[O:28])[O:29][CH3:30])[N:8]([CH2:9]2)[C:10](=[O:26])[CH:11]([NH:18][C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:12][CH2:13][CH2:14][CH2:15][CH:16]=[CH:17]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 178444002methyl 1-[2-[(2-methylpropan-2-yl)oxycarbonylamino]oct-7-enoyl]-4-(4-phenylphenyl)-4-prop-2-enylsulfanylpyrrolidine-2-carboxylateHCID 178524460HCID 178524460, compound

Product 1

HCID 67218046Methyl 3-[(2-methylpropan-2-yl)oxycarbonylamino]-2-oxo-12-(4-phenylphenyl)-11-thia-1-azabicyclo[10.2.1]pentadec-8-ene-14-carboxylate

Sources & evidence

ORD record
ord-6e9df74270cf4fe69b290b188e718055
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…