2-Thiopheneboronic acid → 2-[(2-Chloro-5-thiophen-2-ylpyrimidin-4-yl)amino]butan-1-ol

HRID 837118Notes

Reaction equation

HRID 837118 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Br:14])[c:6]([NH:8][CH:9]([CH2:10][OH:11])[CH2:12][CH3:13])[n:7]1.[s:15]1[c:16]([B:20]([OH:21])[OH:22])[cH:17][cH:18][cH:19]1>>[Cl:1][c:2]1[n:3][cH:4][c:5](-[c:16]2[s:15][cH:19][cH:18][cH:17]2)[c:6]([NH:8][CH:9]([CH2:10][OH:11])[CH2:12][CH3:13])[n:7]1

Participants

3

Reactant 2

HCID 27339602-Thiopheneboronic acidHCID 724550032-[(5-Bromo-2-chloropyrimidin-4-yl)amino]butan-1-ol

Product 1

HCID 724816522-[(2-Chloro-5-thiophen-2-ylpyrimidin-4-yl)amino]butan-1-ol

Sources & evidence

ORD record
ord-940664fe6c0244df9911fd7733b3780d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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