5-(3-Chloro-phenyl)-2-methyl-thiazole-4-carboxylic acid → HCID 178433033, compound

HRID 837236Notes

Reaction equation

HRID 837236 reaction equation
[CH:1]12[NH:2][CH:3]([CH2:7][NH:8][C:9]([C:10]([F:11])([F:12])[F:13])=[O:14])[CH2:4][CH:5]1[CH2:6]2.[Cl:15][c:16]1[cH:17][c:18](-[c:22]2[c:23]([C:28](=[O:29])[OH:30])[n:24][c:25]([CH3:27])[s:26]2)[cH:19][cH:20][cH:21]1>>[CH:1]12[N:2]([C:28]([c:23]3[c:22](-[c:18]4[cH:17][c:16]([Cl:15])[cH:21][cH:20][cH:19]4)[s:26][c:25]([CH3:27])[n:24]3)=[O:29])[CH:3]([CH2:7][NH:8][C:9]([C:10]([F:11])([F:12])[F:13])=[O:14])[CH2:4][CH:5]1[CH2:6]2

Participants

3

Reactant 2

HCID 532711925-(3-Chloro-phenyl)-2-methyl-thiazole-4-carboxylic acidHCID 130019867N-(2-azabicyclo[3.1.0]hexan-3-ylmethyl)-2,2,2-trifluoroacetamide

Product 1

HCID 178433033HCID 178433033, compound

Sources & evidence

ORD record
ord-b471efe611874463b3c3898a5dd9f2d4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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