Potassium Cation → 4-Amino-6-bromo-5-methoxy-2-methylbiphenyl-3-carbonitrile

HRID 837307Notes

Reaction equation

HRID 837307 reaction equation
[Br:7][c:8]1[c:9](-[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:10]([CH3:25])[c:11]([C:23]#[N:24])[c:12]([NH:16][C:17](=[O:18])[C:19]([F:20])([F:21])[F:22])[c:13]1[O:14][CH3:15].[C:1](=[O:2])([O-:3])[O-:4].[CH3:32][OH:33].[K+:5].[K+:6]>>[Br:7][c:8]1[c:9](-[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:10]([CH3:25])[c:11]([C:23]#[N:24])[c:12]([NH2:16])[c:13]1[O:14][CH3:15]

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 887MethanolHCID 19660Carbonate IonHCID 86630811N-(2-Bromo-5-cyano-3-methoxy-6-methylbiphenyl-4-yl)2,2,2-trifluoroacetamide

Product 1

HCID 860974434-Amino-6-bromo-5-methoxy-2-methylbiphenyl-3-carbonitrile

Sources & evidence

ORD record
ord-4b9a3dabecc14358812ec57cdb0399e5
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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