Toluene → (+/-)-3-[(4-Acetyl-2,6-dimethylphenyl)amino]-5-chloro-1-[1-(methoxymethyl)propyl]-2(1H)-pyrazinone

HRID 837343Notes

Reaction equation

[Br:1][c:2]1[cH:3][c:4]([CH3:24])[c:5]([NH:9][c:10]2[c:11](=[O:23])[n:12]([CH:17]([CH2:18][CH3:19])[CH2:20][O:21][CH3:22])[cH:13][c:14]([Cl:16])[n:15]2)[c:6]([CH3:8])[cH:7]1.[CH2:25]([CH3:26])[O:27][C:28]([Sn:29]([CH2:30][CH2:31][CH2:32][CH3:33])([CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH2:40][CH3:41])=[CH2:42].[CH3:120][c:121]1[cH:122][cH:123][cH:124][cH:125][cH:126]1.[cH:43]1[cH:44][cH:45][c:46]([P:47]([Pd:48]([P:49]([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)[c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([P:68]([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[P:87]([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)([c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)[cH:118][cH:119]1>>[c:2]1([C:25]([CH3:26])=[O:27])[cH:3][c:4]([CH3:24])[c:5]([NH:9][c:10]2[c:11](=[O:23])[n:12]([CH:17]([CH2:18][CH3:19])[CH2:20][O:21][CH3:22])[cH:13][c:14]([Cl:16])[n:15]2)[c:6]([CH3:8])[cH:7]1