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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 837371Generated: October 26, 2026

Dimethyl Sulfoxide → 2-{2-[4-(4,5-Dichloro-2-fluoro-phenylamino)-6-nitro-quinazoline-7-yloxy]-ethoxy}-ethanol

https://huagongshe.com/reaction/837371

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
Reactant[SIMe3O]-HCID 3588738—
Reactant2-(2-((Tert-butyldimethylsilyl)oxy)ethoxy)ethanolHCID 11117582—
Reactant4-[(3,4-Dichloro-6-fluorophenyl)amino]-7-fluoro-6-nitroquinazolineHCID 11176185—
Product2-{2-[4-(4,5-Dichloro-2-fluoro-phenylamino)-6-nitro-quinazoline-7-yloxy]-ethoxy}-ethanolHCID 69266955—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-40fbf80d301b4bddbc79496d49a20175
Source noteTest data from https://doi.org/10.1039/C8SC04228D