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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 837462Generated: October 30, 2026

Hydrochloric Acid → 5-[4-(4-Ethoxy2,3-difluorophenoxymethyl)cyclohexyl]tetrahydropyran-2-one

https://huagongshe.com/reaction/837462

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantCyano-borohydrideHCID 498716—
ReactantEthyl 4-[4-(4-ethoxy-2,3-difluorophenoxymethyl)cyclohexyl]5-oxopentanoateHCID 86635748—
Product5-[4-(4-Ethoxy2,3-difluorophenoxymethyl)cyclohexyl]tetrahydropyran-2-oneHCID 66876720—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-26bdb2161c3e4b8cad9763460b6ff83e
Source noteTest data from https://doi.org/10.1039/C8SC04228D