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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 837547Generated: October 25, 2026

Water → 3-[4-[2-Amino-6-[2,2,2-trifluoro-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethoxy]pyrimidin-4-yl]phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid

https://huagongshe.com/reaction/837547

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantEthyl AcetateHCID 8857—
ReactantCarbonate IonHCID 19660—
Reactant1,4-DioxaneHCID 31275—
ReactantCesium cationHCID 104967—
Reactant1-[4-(6-Methoxy-pyridine-2-yl)-phenyl]-2,2,2-trifluoro-ethanolHCID 66743663—
Reactant(2S)-3-(4-(2-Amino-6-chloropyrimidin-4-YL)phenyl)-2-((tert-butoxycarbonyl) amino)propionic acidHCID 74404114—
Product3-[4-[2-Amino-6-[2,2,2-trifluoro-1-[4-(6-methoxy-2-pyridinyl)phenyl]ethoxy]pyrimidin-4-yl]phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acidHCID 66743337—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-2eb5d2bcff5e41c8ac06c3260902e083
Source noteTest data from https://doi.org/10.1039/C8SC04228D