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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 837565Generated: October 29, 2026

Methanol → 3-(Hydroxymethylene)-1'-[4-methoxy-3-(trifluoromethyl)-benzoyl]spiro[chromane-2,4'-piperidine]-4-one

https://huagongshe.com/reaction/837565

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantDiethyl EtherHCID 3283—
ReactantEthyl formateHCID 8025—
ReactantHydrideHCID 166653—
Reactant1'-(4-Methoxy-3-(trifluoromethyl)benzoyl)spiro[chroman-2,4'-piperidin]-4-oneHCID 58551078—
Product3-(Hydroxymethylene)-1'-[4-methoxy-3-(trifluoromethyl)-benzoyl]spiro[chromane-2,4'-piperidine]-4-oneHCID 76828016—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7eadc7cb27ac4da9b8a69b37c6c919f9
Source noteTest data from https://doi.org/10.1039/C8SC04228D