Water → N-[(1S,2S,4S)-4-Amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-2-(2,6-dimethylphenoxy)acetamide

HRID 837594Notes

Reaction equation

HRID 837594 reaction equation
[CH3:1][c:2]1[c:3]([O:4][CH2:5][C:6](=[O:7])[NH:8][CH:9]([CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH:17]([CH2:18][CH:19]([CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[NH:27][C:28]([O:29][C:30]([CH3:31])([CH3:32])[CH3:33])=[O:34])[OH:35])[c:36]([CH3:40])[cH:37][cH:38][cH:39]1.[Cl:42][CH2:43][Cl:44].[OH2:41]>>[CH3:1][c:2]1[c:3]([O:4][CH2:5][C:6](=[O:7])[NH:8][CH:9]([CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH:17]([CH2:18][CH:19]([CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[NH2:27])[OH:35])[c:36]([CH3:40])[cH:37][cH:38][cH:39]1

Participants

4

Reactant 3

HCID 962WaterHCID 6344DichloromethaneHCID 53446070tert-butyl N-[5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate

Product 1

HCID 21706454N-[(1S,2S,4S)-4-Amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-2-(2,6-dimethylphenoxy)acetamide

Sources & evidence

ORD record
ord-8646055661804e01bf89eb710bf3bbf1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…