4-Aminotricyclo[3.3.1.13,7]decane-1-methanol → 3-{2-[1-(3-Hydroxy-2,2-dimethyl-propionyl)-piperidin-4-yl]-ethoxy}-N-(5-hydroxymethyl-adamantan-2-yl)-benzamide
Reaction equation
[NH2:26][CH:27]1[CH:28]2[CH2:29][C:30]3([CH2:37][OH:38])[CH2:31][CH:32]([CH2:33][CH:34]1[CH2:35]3)[CH2:36]2.[OH:1][CH2:2][C:3]([C:4](=[O:5])[N:6]1[CH2:7][CH2:8][CH:9]([CH2:12][CH2:13][O:14][c:15]2[cH:16][c:17]([C:18](=[O:19])[OH:20])[cH:21][cH:22][cH:23]2)[CH2:10][CH2:11]1)([CH3:24])[CH3:25]>>[OH:1][CH2:2][C:3]([C:4](=[O:5])[N:6]1[CH2:7][CH2:8][CH:9]([CH2:12][CH2:13][O:14][c:15]2[cH:16][c:17]([C:18](=[O:19])[NH:26][CH:27]3[CH:28]4[CH2:29][C:30]5([CH2:37][OH:38])[CH2:31][CH:32]([CH2:33][CH:34]3[CH2:35]5)[CH2:36]4)[cH:21][cH:22][cH:23]2)[CH2:10][CH2:11]1)([CH3:24])[CH3:25]Participants
3
Sources & evidence
- ORD record
- ord-2f5ba8b08b514103942a8ff69b0309af
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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