6-(3-Azabicyclo[3.2.0]hept-3-yl)-3-aminopyridine → N-[6-(3-Azabicyclo[3.2.0]hept-3-yl)pyridin-3-yl]-5-trifluoromethyl-1-(3-fluorobenzyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamide
Reaction equation
[CH:25]12[CH2:26][N:27]([c:32]3[cH:33][cH:34][c:35]([NH2:38])[cH:36][n:37]3)[CH2:28][CH:29]1[CH2:30][CH2:31]2.[F:1][C:2]([c:3]1[cH:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([CH2:15][c:16]1[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]1)[c:10]([C:12](=[O:13])[OH:14])[cH:11]2)([F:23])[F:24]>>[F:1][C:2]([c:3]1[cH:4][c:5]2[c:6]([n:7][cH:8]1)[n:9]([CH2:15][c:16]1[cH:17][c:18]([F:22])[cH:19][cH:20][cH:21]1)[c:10]([C:12](=[O:14])[NH:38][c:35]1[cH:34][cH:33][c:32]([N:27]3[CH2:26][CH:25]4[CH:29]([CH2:28]3)[CH2:30][CH2:31]4)[n:37][cH:36]1)[cH:11]2)([F:23])[F:24]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2c93b47465d6429a9d3088e1304f8ab7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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