Methanol → [(3RS,4SR)-3-(3,4-dichloro-phenyl)-4-((RS)-1-hydroxy-ethyl)-pyrrolidin-1-yl]-(6-methoxy-pyridin-3-yl)-methanone

HRID 837707Notes

Reaction equation

HRID 837707 reaction equation
[CH3:27][OH:28].[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH:10]([C:24]([CH3:25])=[O:26])[CH2:11][N:12]([C:14](=[O:15])[c:16]3[cH:17][n:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)[CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8]>>[Cl:1][c:2]1[cH:3][c:4]([CH:9]2[CH:10]([CH:24]([CH3:25])[OH:26])[CH2:11][N:12]([C:14](=[O:15])[c:16]3[cH:17][n:18][c:19]([O:22][CH3:23])[cH:20][cH:21]3)[CH2:13]2)[cH:5][cH:6][c:7]1[Cl:8]

Participants

3

Reactant 2

HCID 887MethanolHCID 671314081-[(3SR,4RS)-4-(3,4-Dichloro-phenyl)-1-(6-methoxy-pyridine-3-carbonyl)-pyrrolidin-3-yl]-ethanone

Product 1

HCID 67130175[(3RS,4SR)-3-(3,4-dichloro-phenyl)-4-((RS)-1-hydroxy-ethyl)-pyrrolidin-1-yl]-(6-methoxy-pyridin-3-yl)-methanone

Sources & evidence

ORD record
ord-be88fd0f4d9b4b5ab0787f1eadf86bd7
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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