Bicarbonate Ion → tert-Butyl 3-bromo-5-(trifluoroacetyl)benzoate

HRID 837815Notes

Reaction equation

HRID 837815 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([CH:15]([C:16]([F:17])([F:18])[F:19])[OH:20])[cH:14]1.[Cl:33][CH2:34][Cl:35].[Na+:21].[Na+:22].[Na+:32].[O-:23][S:24]([O-:25])(=[S:26])=[O:27].[O-:28][C:29]([OH:30])=[O:31]>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[cH:14]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ion3×HCID 1084Thiosulfate ionHCID 6344DichloromethaneHCID 59539580Tert-butyl 3-bromo-5-(2,2,2-trifluoro-1-hydroxyethyl)benzoate

Product 1

HCID 68496903tert-Butyl 3-bromo-5-(trifluoroacetyl)benzoate

Sources & evidence

ORD record
ord-e094b3984ed14d4f85dd1255d7eb7741
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…