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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 837827Generated: October 25, 2026

Acetic Acid → 3-Tert-butoxy-5-chloropyrazine-2-carboxaldehyde

https://huagongshe.com/reaction/837827

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantWaterHCID 962—
ReactantTolueneHCID 1140—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
Reactant2,2,6,6-TetramethylpiperidineHCID 13035—
Reactant2-tert-Butoxy-6-chloropyrazineHCID 22248526—
ReactantButyllithiumHCID 178418339—
Product3-Tert-butoxy-5-chloropyrazine-2-carboxaldehydeHCID 22248202—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-be4a8223856c4fb3ba4636277c0c0404
Source noteTest data from https://doi.org/10.1039/C8SC04228D