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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 837919Generated: November 1, 2026

Water → Methyl 2-Chloro-5-fluoro-6-pyrrolidin-1-ylnicotinate

https://huagongshe.com/reaction/837919

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantPyrrolidineHCID 31268—
ReactantMethyl 2,6-dichloro-5-fluoronicotinateHCID 2775354—
ProductMethyl 2-Chloro-5-fluoro-6-pyrrolidin-1-ylnicotinateHCID 57815196—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-6f4ce6da7dc043fca7a25ffce3b51214
Source noteTest data from https://doi.org/10.1039/C8SC04228D