Ethanol → 5-Chloro-6-{4-[2-chloro-6-(4-fluoro-phenyl)-pyrimidin-4-yl]piperazin-1-yl}-nicotinic acid ethyl ester

HRID 838004Notes

Reaction equation

[CH2:21]([CH3:22])[O:23][C:24]([c:25]1[cH:26][n:27][c:28]([N:32]2[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]2)[c:29]([Cl:31])[cH:30]1)=[O:38].[CH3:39][CH2:40][OH:41].[Cl:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:5][c:6]([Cl:8])[n:7]1.[Na+:20].[O-:16][C:17]([OH:18])=[O:19]>>[Cl:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([F:15])[cH:13][cH:14]2)[cH:5][c:6]([N:35]2[CH2:34][CH2:33][N:32]([c:28]3[n:27][cH:26][c:25]([C:24]([O:23][CH2:21][CH3:22])=[O:38])[cH:30][c:29]3[Cl:31])[CH2:37][CH2:36]2)[n:7]1