Methyl 2-(2-(4-nitrophenoxy)ethoxy)acetate → HCID 59253936, compound

Participants

Reaction Steps

[2-(4-Nitrophenoxy)ethoxy]acetic acid methyl ester 42 (1 g, 3.9 mmol) was dissolved in anhydrous ethyl acetate (20 ml). Palladium on carbon (10%, 0.1 g) was added and the mixture stirred under a hydrogen atmosphere using a balloon for 30 mins. The cat-alyst was filtered, the filtrate concentrated, hexane (3 ml) added, and the solid filtered to give 43 (625 mg, 70.9%) as a light brown powder with a m.p. between 51-52.5° C.

Provenance & Evidence