Hydrochloric Acid → 1,8-Diazabicyclo[5.4.0]undec-7-ene hydrochloride

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Reaction Steps

A flame dried flask was charged with DBU (1.0 g, 6.56 mmol), ether (20 mL) and a stirbar under dry nitrogen atmosphere. With vigorous stirring, a 1M ethereal HCl solution (6.6 mL, 6.6 mmol) was added to form a white precipitate. Stirring was continued for 1 hour then excess solvent was decanted to yield 1.1 g (90%). The salt was then dried under high vacuum.

Provenance & Evidence