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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 838542Generated: October 25, 2026

Water → Biphenyl-4-carboxylic acid {2-[4-(2-bromo-5-nitro-benzoyl)-piperazin-1-yl]-2-oxo-ethyl}-amide

https://huagongshe.com/reaction/838542

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Bromo-5-nitrobenzoic acidHCID 243025—
ReactantBiphenyl-4-carboxylicacid (2-oxo-2-piperazin-1-yl-ethyl)-amideHCID 57855677—
ProductBiphenyl-4-carboxylic acid {2-[4-(2-bromo-5-nitro-benzoyl)-piperazin-1-yl]-2-oxo-ethyl}-amideHCID 59559617—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d098b1bae18a4418a4a095afe0e10715
Source noteTest data from https://doi.org/10.1039/C8SC04228D