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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 838567Generated: October 30, 2026

Methanol → N-[1-(1,4-dioxaspiro[4.5]decan-8-yl)piperidin-4-yl]-N-(4-fluorophenyl)acetamide

https://huagongshe.com/reaction/838567

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantBorohydrideHCID 28123—
Reactant1,4-Dioxaspiro[4.5]decan-8-oneHCID 567415—
ReactantHCID 18539208HCID 18539208—
ProductN-[1-(1,4-dioxaspiro[4.5]decan-8-yl)piperidin-4-yl]-N-(4-fluorophenyl)acetamideHCID 59434279—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-025c308a271c47c6aa9c006cd27e7386
Source noteTest data from https://doi.org/10.1039/C8SC04228D