Pyridine → N-Acetyloxymethyl-3-(2-chlorophenyl)-4-cyanopyrrole

HRID 838672Notes

Reaction equation

HRID 838672 reaction equation
[CH3:17][N:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][n:24]1)[CH3:25].[CH3:26][C:27](=[O:28])[O:29][C:30](=[O:31])[CH3:32].[OH:1][CH2:2][n:3]1[cH:4][c:5](-[c:10]2[c:11]([Cl:16])[cH:12][cH:13][cH:14][cH:15]2)[c:6]([C:8]#[N:9])[cH:7]1.[cH:33]1[cH:34][cH:35][n:36][cH:37][cH:38]1>>[O:1]([CH2:2][n:3]1[cH:4][c:5](-[c:10]2[c:11]([Cl:16])[cH:12][cH:13][cH:14][cH:15]2)[c:6]([C:8]#[N:9])[cH:7]1)[C:27]([CH3:26])=[O:28]

Participants

5

Reactant 4

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 218852-DimethylaminopyridineHCID 202487964-(2-Chlorophenyl)-1-(hydroxymethyl)-1H-pyrrole-3-carbonitrile

Product 1

HCID 20248792N-Acetyloxymethyl-3-(2-chlorophenyl)-4-cyanopyrrole

Sources & evidence

ORD record
ord-32221940fb1846ed8453b4eda18e670c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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