2,4-Octanedione, 1,1,1-trifluoro-7-methyl- → HCID 20324949, compound

HRID 838853Notes

Reaction equation

HRID 838853 reaction equation
[NH2:1][C:2]1[CH:6]=[CH:5][NH:4][N:3]=1.[F:7][C:8]([F:20])([F:19])[C:9](=O)[CH2:10][C:11](=O)[CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15]>CCO>[CH2:12]([C:11]1[N:3]2[N:4]=[CH:5][CH:6]=[C:2]2[N:1]=[C:9]([C:8]([F:7])([F:19])[F:20])[CH:10]=1)[CH2:13][CH:14]([CH3:16])[CH3:15]

Participants

4

Reactant 2

HCID 842482,4-Octanedione, 1,1,1-trifluoro-7-methyl-HCID 178418806HCID 178418806, compound

Product 1

HCID 20324949HCID 20324949, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 2.0 gm of 3-aminopyrazole (0.024 mol) in 50 ml EtOH was refluxed with 5.0 gm of 1,1,1, -trifluoro-7-methyl-2,4-octanedione (0.024 mol) for 2 hours. The mixture was evaporated and distilled to yield 1.6 gm (48%) of a slightly yellowish oil, b.p. 103°-105°/0.5 mm.

Workup

  1. customThe mixture was evaporated
  2. distillationdistilled
  3. customto yield 1.6 gm (48%) of a slightly yellowish oil, b.p. 103°-105°/0.5 mm

Sources & evidence

ORD record
ord-fdcc07c04dca48a1a3fb2c8197043970
Source dataset
uspto-grants-1978_06
Patent number
US04093617

Reaction notes

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