HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-Hydroxy-4-(1-naphthyl)coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Resorcinol | HCID 5054 | — |
| Reactant | Ethyl 3-(naphthalen-8-yl)-3-oxopropanoate | HCID 2760157 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-Hydroxy-4-(1-naphthyl)coumarin | HCID 23330744 | — |
Reaction Steps
A solution of resorcinol (4.84g., 0.041 moles) and ethyl 1-naphthoylacetate (10g., 0.041 moles) in ethanol (50 ml.) was saturated with hydrogen chloride at room temperature (cooling with ice/water) and left to stand in a stoppered flask for 24 hours. The solution was filtered to give the required coumarin as an orange solid (7.8g., 66%, m.p. 292°-295° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04093631 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-c4c38b015fc8448499f859f391604dbb |
| Source note | uspto-grants-1978_06 |