HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-Methyl-N'-hydroxy-N"-[4-(4-imidazolyl)butyl]guanidine dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | N,S-dimethyl-N'-[4-(4-imidazolyl)butyl]isothiourea | HCID 178484951 | — |
| Reactant | N-[4-(1H-imidazol-5-yl)butyl]-N'-methylcarbamimidothioic acid | HCID 178486108 | — |
| Product | N-Methyl-N'-hydroxy-N"-[4-(4-imidazolyl)butyl]guanidine dihydrochloride | HCID 178484950 | — |
Reaction Steps
When N-methyl-N'-[4-(4-imidazolyl)butyl]thiourea is reacted with methanolic hydrogen chloride by the procedure of Example 1(i) the product is N,S-dimethyl-N'-[4-(4-imidazolyl)butyl]isothiourea which on treatment with hydroxylamine by the procedure of Example 1(ii) gives the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04093729 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-3e664da6134e4171ae1d49a6eab6ba5e |
| Source note | uspto-grants-1978_06 |