反应详情

To 41.7 g. (0.15 mol.) of phthalimidomethanesulfonic acid potassium salt in 220 ml. of dry benzene is added 22.5 g. (0.132 mol.) of phosphorus pentachloride. The reaction mixture is refluxed on a steam bath for one hour, then an additional 22.5 g. of phosphorus pentachloride is added and heating is continued for 1.5 hours. The reaction mixture is evaporated to dryness, crushed ice is added to the residue and the slurry is filtered. The product is washed with water to give phthalimidomethanesulfonyl chloride.

1. temperatureThe reaction mixture is refluxed on a steam bath for one hour
2. temperatureheating
3. customThe reaction mixture is evaporated to dryness
4. customcrushed ice
5. additionis added to the residue
6. filtrationthe slurry is filtered
7. washThe product is washed with water