3,5-Heptanedione → HCID 514327, compound

HRID 839160Notes

Reaction equation

HRID 839160 reaction equation
[Li].CCC(=O)CC(=O)CC.C([O:18][C:19]1[CH:20]=[C:21]([CH2:33][CH2:34][CH:35]=[CH:36][CH2:37][CH2:38][CH:39]([C:44](=[O:47])[CH2:45][CH3:46])[C:40](=[O:43])[CH2:41][CH3:42])[CH:22]=[CH:23][C:24]=1[O:25]CC1C=CC=CC=1)C1C=CC=CC=1>>[OH:18][C:19]1[CH:20]=[C:21]([CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH:39]([C:40](=[O:43])[CH2:41][CH3:42])[C:44](=[O:47])[CH2:45][CH3:46])[CH:22]=[CH:23][C:24]=1[OH:25]

Participants

4

Reactant 3

HCID 819233,5-HeptanedioneHCID 3028194LithiumHCID 53736066HCID 53736066, compound

Product 1

HCID 514327HCID 514327, compound

Procedure

[I; Ar is 3,4-(HO)2C6H3, R0 is H, R' and R" are CH3CH2CO, Y is CH2CH2CH2CH2 ] was prepared from the compound of Preparation D17 and the lithium salt of 3,5-heptanedione, followed by catalytic hydrogenation of the resulting 4-[6-(3,4-dibenzyloxyphenyl)-3-hexenyl]-3,5-heptanedione. It was obtained as an amber oil after chromatography.

Workup

  1. customwas prepared from the compound of Preparation D17
  2. customIt was obtained as an amber oil after chromatography

Sources & evidence

ORD record
ord-b9ab1b45b83d42009cdff0136cdeb468
Source dataset
uspto-grants-1978_06
Patent number
US04093736

Reaction notes

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