HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 5-(5-nitrofuran-2-yl)-1H-pyrazole-4-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 1-Methoxycarbonyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde-ethyleneacetal | HCID 20326046 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-(5-nitrofuran-2-yl)-1H-pyrazole-4-carbaldehyde | HCID 178519881 | — |
Reaction Steps
React 3.1 g of 1-methoxycarbonyl-3-(5-nitro-2-furyl)pyrazole-4-carboxaldehyde-ethyleneacetal in 50 ml of dioxan and 25 ml of water with 1.73 g of piperidine for 20 minutes at room temperature (20° C) and then proceed according to the method of part (a) above to obtain 3-(5-nitro-2-furyl)-1H-pyrazole-4-carboxaldehyde with a melting point of 185° to 187° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04093812 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-0701e83ff65d4d4bba6c4d0922f88c75 |
| Source note | uspto-grants-1978_06 |