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HRID839221

反应详情

EQUATION

反应方程式

HRID 839221 的结构方程式

REACTANTS

反应物

2
结构：O=S(Cl)Cl
HCID24386

Thionyl chloride

Cl2OS

结构：O=[N+]([O-])c1ccc(-c2nn(-c3ccccc3)cc2C=NO)o1
HCID54343732

N-{[3-(5-Nitrofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl]methylidene}hydroxylamine

C14H10N4O4

PRODUCTS

生成物

1
结构：N#Cc1cn(-c2ccccc2)nc1-c1ccc([N+](=O)[O-])o1
HCID20326158

3-(5-Nitrofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbonitrile

C14H8N4O3

收率 96%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)(Cl)Cl
溶剂HCID5943

Carbon tetrachloride

CCl4

PROCEDURE

实验过程

Add 9.4 ml of thionyl chloride to a suspension of 32.6 g of finely-ground 3-(5-nitro-2-furyl)-1-phenylpyrazole-4-carboxaldehydeoxime in 250 ml of carbon tetrachloride at 60° to 65° C. Stir the resulting admixture for 1.5 hours at this temperature and for 2 hours under reflux. Separate the formed precipitate by vacuum filtration at room temperature. Wash the filter residue (precipitate) with carbon tetrachloride and dry to obtain a 96% yield of 3-(5-nitro-2-furyl)-1-phenylpyrazole-4-carbonitrile [m.p. 190° to 192° C].

WORKUP

后处理

  1. temperaturefor 2 hours under reflux
  2. customSeparate the formed precipitate
  3. filtrationby vacuum filtration at room temperature
  4. washWash the filter residue (precipitate) with carbon tetrachloride
  5. customdry