huagongshe.com
HRID839223

反应详情

EQUATION

反应方程式

HRID 839223 的结构方程式

REACTANTS

反应物

2
结构：N
HCID222

Ammonia gas

H3N

结构：O=Cc1cn(-c2ccccc2)nc1-c1ccc([N+](=O)[O-])o1
HCID20326255

3-(5-Nitrofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde

C14H9N3O4

PRODUCTS

生成物

1
结构：N#Cc1cn(-c2ccccc2)nc1-c1ccc([N+](=O)[O-])o1
HCID20326158

3-(5-Nitrofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbonitrile

C14H8N4O3

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Mn+4].[O-2].[O-2]
催化剂HCID178418406

未命名化合物

结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

Boil (under reflux) 5 g of 3-(5-nitro-2-furyl)-1-phenylpyrazole-4-carboxaldehyde together with 7.6 g of activated manganese dioxide and 300 ml of toluene with the introduction of ammonia using a water-trap. Filter after 5 hours and then evaporate the filtrate to dryness in vacuo before recrystallizing three times from dimethylformamide and water to obtain 3-(5-nitro-2-furyl)-1-phenylpyrazole-4-carbonitrile [m.p. 190° to 192° C].

WORKUP

后处理

  1. filtrationFilter after 5 hours
  2. customevaporate the filtrate to dryness in vacuo
  3. custombefore recrystallizing three times from dimethylformamide and water