HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazinecarboxylic acid, ethyl ester → 3-(5-Nitro-2-furyl)-1-(2-pyridyl)pyrazole-4-carboxaldehyde-ethoxycarbonylhydrazone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazinecarboxylic acid, ethyl ester | HCID 20064 | — |
| Reactant | 3-(5-Nitrofuran-2-yl)-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde | HCID 20326164 | — |
| Catalyst | Acetic Acid | HCID 176 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(5-Nitro-2-furyl)-1-(2-pyridyl)pyrazole-4-carboxaldehyde-ethoxycarbonylhydrazone | HCID 53880645 | 97% |
Reaction Steps
Heat 0.6 g of 3-(5-nitro-2-furyl)-1-(2-pyridyl)pyrazole-4-carboxaldehyde together with 0.27 g of ethylcarbazate and 2 drops of glacial acetic acid in 8 ml of ethanol for 1.5 hours at boiling point. Cool the resulting product for a 97% yield of 3-(5-nitro-2-furyl)-1-(2-pyridyl)pyrazole-4-carboxaldehyde-ethoxycarbonylhydrazone [m.p. 215° to 216° C (with decomposition) from toluene].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04093812 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-87e1316c0710435b8c2e2b1c6bf262e9 |
| Source note | uspto-grants-1978_06 |