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Water → 3-(5-nitro-2-furyl)-1,N'-diphenylpyrazole-4-carbohydrazide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Phenylhydrazine | HCID 7516 | — |
| 反応物 | 3-(5-Nitrofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbonyl chloride | HCID 20325933 | — |
| 反応物 | Npc112006 | HCID 21965192 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 3-(5-nitro-2-furyl)-1,N'-diphenylpyrazole-4-carbohydrazide | HCID 20326104 | — |
反応手順
Add a solution of 1.0 g of 3-(5-nitro-2-furyl)-1-phenylpyrazole-4-carboxylic acid chloride in 50 ml of pyridine dropwise to a solution of 0.31 ml of phenyl hydrazine in 5 ml of pyridine and stir the resulting reaction mixture at room temperature for 4 hours. Pour the thus-produced solution onto ice and water and chromatograph on silica gel with benzene/ethanol (9:1) to obtain 3-(5-nitro-2-furyl)-1,N'-diphenylpyrazole-4-carbohydrazide.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04093812 |
| 出典データセット | uspto-grants-1978_06 |
| ORD ID | ord-f708c25433c149f2be8ac9c3234d74ce |
| 出典メモ | uspto-grants-1978_06 |