Hydrochloric Acid → HCID 20326032, compound

Participants

Reaction Steps

To prepare the starting material, heat 1 g of 4-(5-nitro-2-furyl)-1-phenylpyrazole-4-carboxylic acid azide in 15 ml of absolute dioxane for 1 hour at 90° C. After gas formation has finished, add the solution of the produced [3-(5-nitro-2-furyl)-1-phenyl-4-pyrazolyl]isocyanate dropwise to 4 ml of concentrated hydrochloric acid and then stir the resulting admixture overnight at from 40° to 45° C. Cool the thus-prepared material and draw off the formed precipitate to obtain 4-amino-3-(5-nitro-2-furyl)-1-phenylpyrazole hydrochloride [m.p. 211° to 213° C (with decomposition)] with the yield of 88%.

Provenance & Evidence