Morpholine → HCID 18384073, compound

HRID 839252Notes

Reaction equation

HRID 839252 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8](Cl)=[C:7]([N+:12]([O-:14])=[O:13])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH:15]1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1>>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)=[C:7]([N+:12]([O-:14])=[O:13])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 8083MorpholineHCID 119617424-tert-Butyl-1-chloro-2-nitrobenzene

Product 1

HCID 18384073HCID 18384073, compoundYield 95%

Procedure

4-tert-Butyl-2-nitrochlorobenzene (19 g.; 68 mmoles) and morpholine (30 g.; 340 mmoles) were heated at 90° C. for 40 hours. The mixture was then poured into ice water. The yellow solid precipitate was collected by filtration (95% yield) and found to melt at 58°-60° C.

Workup

  1. filtrationThe yellow solid precipitate was collected by filtration (95% yield)
  2. customto melt at 58°-60° C.

Sources & evidence

ORD record
ord-db8f8dec28c64f63b27e7ba955861370
Source dataset
uspto-grants-1978_06
Patent number
US04094662

Reaction notes

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