HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 839355Generated: October 30, 2026
Benzoic Acid → 3-(2,4-Bis(diethylamino)phenyl)-3-(4-(diethylamino)phenyl)phthalide
https://huagongshe.com/reaction/839355
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzoic Acid | HCID 243 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | N~1~,N~1~,N~3~,N~3~-Tetraethylbenzene-1,3-diamine | HCID 19382815 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-(2,4-Bis(diethylamino)phenyl)-3-(4-(diethylamino)phenyl)phthalide | HCID 53909156 | — |
Reaction Steps
A mixture of 2-(4-diethylamino)benzoyl)benzoic acid (5.94 g.), N,N,N',N'-tetraethyl-m-phenylenediamine (4.84 g.) and acetic anhydride (3 ml.) was heated at 70° C. Addition of methanol (20 ml.) afforded 3-(2,4-bis(diethylamino)phenyl)-3-(4-(diethylamino)phenyl)phthalide (I: X = Y4 = (CH3CH2)2N, Y2 = Z4 = Z5 = Z6 = Z7 = H) (7.1 g., 135°-137° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04094877 |
|---|
| Source dataset | uspto-grants-1978_06 |
|---|
| ORD ID | ord-8f280f3f582046f59e440fb18bc6241b |
|---|
| Source note | uspto-grants-1978_06 |
|---|
