HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoic anhydride → HCID 70616878, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoic anhydride | HCID 7167 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 14823699 | HCID 14823699 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 70616878 | HCID 70616878 | — |
Reaction Steps
A solution of 9-fluoro-11β-hydroxy-17-(methylthio)androsta-1,4,16-trien-3-one (100 mg, see Example 1B) in 30 ml of xylene containing 4.0 g of benzoic anhydride and 300 mg of sodium methoxide is stirred at 130° C for 48 hours. The product is then isolated and chromatographed over silica gel to yield 80 mg of the title compound, melting point 220°-222° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04094840 |
| Source dataset | uspto-grants-1978_06 |
| ORD ID | ord-3ee29a8d4b7649f581bf024c7cd36fcd |
| Source note | uspto-grants-1978_06 |